{"id":1754,"date":"2021-11-09T16:31:22","date_gmt":"2021-11-09T16:31:22","guid":{"rendered":"https:\/\/lumed.ca\/?post_type=nouvelle&#038;p=1754"},"modified":"2021-11-09T16:31:23","modified_gmt":"2021-11-09T16:31:23","slug":"something-new-at-lumed-in-the-antimicrobial-stewardship-module-apss","status":"publish","type":"nouvelle","link":"https:\/\/lumed.ca\/en\/nouvelles\/something-new-at-lumed-in-the-antimicrobial-stewardship-module-apss\/","title":{"rendered":"Something new at Lumed, in the antimicrobial stewardship module (APSS)."},"content":{"rendered":"\n<p>A calculator has been added to provide a decision support tool to optimize the efficacy and limit the toxicity of colistin. The advantage of the calculator is its availability from a patient&#8217;s review screen and the importation of the demographic and clinical data necessary for the calculations. The calculator is harmonized with the recommendations of the latest international consensus guidelines.\u00a0<em>(Pharmacotherapy 2019; 39 (1): 10\u201339).<\/em><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/lumed.ca\/wp-content\/uploads\/2021\/11\/image-3-1024x476.png\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"476\" src=\"https:\/\/lumed.ca\/wp-content\/uploads\/2021\/11\/image-3-1024x476.png\" alt=\"\" class=\"wp-image-1755\" srcset=\"https:\/\/lumed.ca\/wp-content\/uploads\/2021\/11\/image-3-1024x476.png 1024w, https:\/\/lumed.ca\/wp-content\/uploads\/2021\/11\/image-3-300x140.png 300w, https:\/\/lumed.ca\/wp-content\/uploads\/2021\/11\/image-3-768x357.png 768w, https:\/\/lumed.ca\/wp-content\/uploads\/2021\/11\/image-3-1536x714.png 1536w, https:\/\/lumed.ca\/wp-content\/uploads\/2021\/11\/image-3.png 1632w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n\n\n<p>Since its reintroduction, significant confusion remains regarding colistin use due to differences in the available formulations and the different conventions used to describe the dosage [milligrams (mg) or international units (IU) of colistin base (CBA) or colistin methanesulfonate (CMS)]. \u00a0As a reminder, colistin is administered as an inactive prodrug, colistimethate, also known as colistin methanesulfonate [CMS]. A lack of clarity remained about how optimally to utilize and dose colistin, a highly nephrotoxic and neurotoxic agent. Given the narrow therapeutic windows of colistin, the calculator and the dosages included in the knowledge base should provide a practical framework for clinicians who use colistin in the treatment of infections caused by multidrug-resistant (MDR) gram-negative pathogens.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A calculator has been added to provide a decision support tool to optimize the efficacy and limit the toxicity of colistin. The advantage of the calculator is its availability from a patient&#8217;s review screen and [&hellip;]<\/p>\n","protected":false},"author":10,"template":"","restrain":[],"placement":[],"news_cat":[],"class_list":["post-1754","nouvelle","type-nouvelle","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/lumed.ca\/en\/wp-json\/wp\/v2\/nouvelle\/1754","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lumed.ca\/en\/wp-json\/wp\/v2\/nouvelle"}],"about":[{"href":"https:\/\/lumed.ca\/en\/wp-json\/wp\/v2\/types\/nouvelle"}],"author":[{"embeddable":true,"href":"https:\/\/lumed.ca\/en\/wp-json\/wp\/v2\/users\/10"}],"version-history":[{"count":5,"href":"https:\/\/lumed.ca\/en\/wp-json\/wp\/v2\/nouvelle\/1754\/revisions"}],"predecessor-version":[{"id":1761,"href":"https:\/\/lumed.ca\/en\/wp-json\/wp\/v2\/nouvelle\/1754\/revisions\/1761"}],"wp:attachment":[{"href":"https:\/\/lumed.ca\/en\/wp-json\/wp\/v2\/media?parent=1754"}],"wp:term":[{"taxonomy":"restrain","embeddable":true,"href":"https:\/\/lumed.ca\/en\/wp-json\/wp\/v2\/restrain?post=1754"},{"taxonomy":"placement","embeddable":true,"href":"https:\/\/lumed.ca\/en\/wp-json\/wp\/v2\/placement?post=1754"},{"taxonomy":"news_cat","embeddable":true,"href":"https:\/\/lumed.ca\/en\/wp-json\/wp\/v2\/news_cat?post=1754"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}